Some of these drugs need to be shaken before use. Be sure you know if this product needs to be shaken before using it.

Brand names: Artificial Tears, Biolle Gel Tears, Biolle Tears, GenTeal, Lubricating Plus Eye Drops,Cases with moderate to high increase in osmolarity and significant ocular surface staining invariably require prescription based anti-inflammatory drops. The importance of lifestyle and dietary modification should be emphasized during counseling and is helpful for all types of dry eye patients. Warm compresses and lid hygiene are also critical for meibomian gland dysfunction. Use of gels and nighttime ointments is also an option for moderate cases. Ointments are exclusively for nighttime use but some gel formulations (Refresh Liquigel ®, Refresh Celluvisc ®, Refresh Optive Gel ®, Systane Gel Drops ®, Blink Gel Tears ®) can be used during both the day and nighttime. Patients need to be counselled on transient blurring of vision with the daytime use of gels. Apply 1-2 drops into each eye, one or more times a day every few hours or otherwise stated by an healthcare professional.

As we age it is common to experience dry, tired, and irritated eyes due to the amount of tears our eyes produce naturally reducing. Changes in health conditions, certain medications and hormone balance during and after the menopause can also have an impact on eyes becoming more prone to drying out. Our older eye treatment drops are designed to deliver fast, effective, and long-lasting relief from the pain of dry eyes. They contain patented cross-linked hyaluronic acid 0.3%, which means they have a higher viscosity than other eye drops and can keep eyes lubricated for longer. Refreshing, calming ingredients Adverse reactions or quality problems experienced with the use of this product may be reported to the FDA's MedWatch Adverse Event Reporting program either online, by regular mail or by fax. The Harvard Drug Group, LLC Issues Voluntary Nationwide Recall of Certain Rugby® Laboratories Brand Eye Drops Supplied by Velocity Pharma, LLC Due to Potential Risk of Eye Infections Oct 31, 2023 | Audience: Consumer, Health Professional, Ophthalmology, PharmacyNovember 13, 2023– Mumbai, Maharashtra, Kilitch Healthcare India Limited is voluntarily recalling the eye drops products listed in the table below to the consumer level with all lots within expiry with expiration dates ranging from November, 2023 to September, 2025 for all the below mentioned products. These products are being recalled due to potential safety concerns after FDA investigators found insanitary conditions. These products are available as over the counter (OTC) products used for temporary relief of burning and irritation due to dryness of the eye, for use as a protectant against further irritation or to relieve dryness of the eye, and/or to relieve redness of the eye due to minor eye irritations. All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical Preservative-free eye drops. This type has fewer additives and is generally recommended if you apply artificial tears more than four times a day, or if you have moderate or severe dry eyes. Preservative-free eye drops may come in single-dose vials. Tell all of your health care providers that you take TheraTears Nighttime (carboxymethylcellulose). This includes your doctors, nurses, pharmacists, and dentists.

If you are allergic to TheraTears Nighttime (carboxymethylcellulose); any part of TheraTears Nighttime (carboxymethylcellulose); or any other drugs, foods, or substances. Tell your doctor about the allergy and Cardinal Health, Inc. Issues Voluntary Nationwide Recall of Certain LEADER™ Brand Eye Drops Supplied by Velocity Pharma, LLC Due to Potential Risk of Eye Infections Oct 31, 2023 | Audience: Consumer, Health Professional, Ophthalmology, Pharmacy As well as helping your eyes to feel better, these drops can also make them look brighter and healthier. The product contains Euphrasia, also known as eyebright. This natural plant extract supports eye whitening. A lasting soothing effectThese are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical

Demulcents are the primary active ingredient for artificial tears. Our data analysis shows that there are primarily four categories of artificial tears to select from based on the demulcent present in them. Two brands contain CMC as demulcents, with Thera Tears ® containing the lowest concentration of CMC at 0.25%. These drops are a great option for patients with milder symptoms of dry eye who better tolerate lower concentrations of CMC. Thera Tears ® are available in multidose vial containing the vanishing preservative sodium perborate or as preservative-free single application. Thera Tears extra ® with 0.25% CMC plus trehalose as an additional ingredient are available only as sodium perborate preservative containing multidose vial. Sodium perborate, also known as Dequest, is a vanishing type of preservative. In solution, it is converted to hydrogen peroxide and causes the bactericidal effect by oxidative stress-mediated denaturation of bacterial proteins. Upon instillation into an eye, it is converted to oxygen and water by the enzyme catalase. Sodium perborate is less toxic than benzalkonium chloride but not completely innocuous [ 25, 26]. Therefore, preservative-free Thera Tears ® should be preferred if a patient needs more than four applications per day.Refresh ® brand of artificial tears have several formulations containing 0.5% CMC alone, with additional demulcents and biologically active excipients like osmoprotectants erythritol, l-carnitine, and trehalose. L-carnitine and erythritol have been shown to attenuate hyperosmolar stress-mediated increase in MAP kinases, pro-inflammatory cytokines, and matrix metalloproteases in corneal epithelial cells [ 27, 28, 29, 30]. Clinical studies demonstrate that artificial tears containing L-carnitine and erythritol reduce tear osmolarity and provide symptomatic relief [ 31, 32, 33]. Studies in animal models of dry eye and clinical studies with trehalose containing eye drops demonstrate many beneficial effects, including increased tear production, tear stabilization, reduced corneal staining, and a decrease in corneal epithelial cell apoptosis [ 34, 35, 36, 37]. Humectant sodium hyaluronate in Refresh ®, Oasis ® and Blink ® tears can offer significant additional relief in dry eye in preventing or treating corneal epithelial damage since in vitro studies demonstrate that sodium hyaluronate promotes corneal epithelial cell migration and proliferation, thus facilitating healing [ 38, 39, 40]. Topical application of sodium hyaluronate in rabbits and mice has been shown to promote wound healing and relieve dry eye symptoms [ 41, 42]. Castor oils and flaxseed oil in some Refresh ® Brand tears will offer the additional benefit of reduced tear evaporation in patients with evaporative dry eye. Purite, the preservative present in Refresh ® brand artificial tears, is stabilized oxychloro complex (SOC) containing 99.5% chlorite, 0.5% chlorate. In solution, its bactericidal action is mediated by the oxidizing action of chlorine dioxide free radical. It belongs to the vanishing class of artificial tears since upon instillation, it is converted to sodium chloride, oxygen, and water [ 43, 44]. Animal studies demonstrate that purite is significantly less toxic to corneal epithelium compared to benzalkonium chloride but has some degree of detrimental effect compared to preservative-free artificial tears [ 43, 44, 45, 46, 47]. Given the wide variety of options, a patient can be started on Refresh ® tears with CMC alone either with or without preservatives depending upon the frequency of instillation required and if the dry eye relief is inadequate, Refresh ® tears with additional biologically active excipients can be tried. Hydroxypropyl guar is a viscous protein polymer derived from beans. Upon instillation, hydroxypropyl guar forms a soft gel with increased viscosity at the tear pH. It mimics the properties of mucin layer by strengthening the attachment of the aqueous layer to the mucins and promotes the retention of other demulcents [ 20, 21]. It has also been shown to stabilize the tear film. Hydroxypropyl guar is present in all Systane ® brand artificial tears ( Table 3).